Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8C43L)

• Drug Name: 2,3-dioxoindoline-7-carboxylic acid Drug Info
• Synonyms: 2,3-dioxoindoline-7-carboxylic acid; 25128-35-2; Isatin-7-carboxylic acid; 2,3-DIOXO-2,3-DIHYDRO-1H-INDOLE-7-CARBOXYLIC ACID; 2,3-dioxo-1H-indole-7-carboxylic Acid; CHEMBL375078; 1H-INDOLE-7-CARBOXYLIC ACID, 2,3-DIHYDRO-2,3-DIOXO-; 2,3-dioxo-1H-benzo[d]azolidine-7-carboxylic acid; 2,3-Dioxoindoline-7-carboxylicacid; 7-isatincarboxylic acid; PubChem24310; AC1MCVF6; Isatin-based compound, 46; AC1Q72QN; SCHEMBL1742133; BDBM22826; CTK1A1532; DTXSID00381427; ROODQCZSWXEDJL-UHFFFAOYSA-N; MolPort-000-144-864; ZINC2496760; KS-00000FO0

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 2779383
  CAS Number: CAS 25128-35-2
  TTD Drug ID: DM8C43L

Molecule-Related Drug Atlas

Drug(s) Targeting Bacterial DNA ligase (Bact ligA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
5-(methylthio)thiophene-2-carboxylic acid	DMYLIX9	Discovery agent	N.A.	Investigative	[1]
7-(4-methoxyphenyl)pteridine-2,4-diol	DMLIYUJ	Discovery agent	N.A.	Investigative	[1]
(2-hydroxyphenyl)(4-hydroxyphenyl)methanone	DMEZNXS	Discovery agent	N.A.	Investigative	[1]
3-amino-2-(benzylideneamino)-5-mercaptophenol	DMF3DBE	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial DNA ligase (Bact ligA)	TTGX0HR	DNLJ_ECOLI	Inhibitor	[1]

References

• [1] Identification and validation of human DNA ligase inhibitors using computer-aided drug design. J Med Chem. 2008 Aug 14;51(15):4553-62.