Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8MGSH)

Drug Name

GPRC5D CAR-T cell therapy Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Multiple myeloma	2A83	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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Drug(s) Targeting G-protein coupled receptor C 5D (GPRC5D)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Talquetamab	DMXRENI	Multiple myeloma	2A83	Approved	[3]
RG6234	DMYUSOJ	Multiple myeloma	2A83	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled receptor C 5D (GPRC5D)	TTHRAPJ	GPC5D_HUMAN	Not Available	[2]

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References

1	Clinical pipeline report, company report or official report of Bristol-Myers Squibb.
2	GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells. Sci Transl Med. 2019 Mar 27;11(485):eaau7746.
3	FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761342
4	Clinical pipeline report, company report or official report of Roche