Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8NA4M)

Drug Name

AVT-02 UE Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Skin infection	1F28-1G0Z	Discontinued in Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Signal transducer and activator of transcription 1 (STAT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Platinum IV complexe 1	DM8OYI4	N. A.	N. A.	Patented	[3]
PMID26394986-Compound-10	DMP8RQ4	N. A.	N. A.	Patented	[3]
Oxazole derivative 1	DM7Y2RL	N. A.	N. A.	Patented	[3]
Peptidomimetic analog 5	DMF0DE2	N. A.	N. A.	Patented	[3]
Peptide analog 8	DMFG7A8	N. A.	N. A.	Patented	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Signal transducer and activator of transcription 1 (STAT1)	TTN7R6K	STAT1_HUMAN	Inhibitor	[2]

------------------------------------------------------------------------------------

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025413)
2	Avontec Announces Results of a Multiple Dose Clinical Phase I Study with Its Drug Candidate AVT-02 UE Ointment After Topical Treatment in Male Healthy Volunteers. Avontec. 2008.
3	A STAT inhibitor patent review: progress since 2011.Expert Opin Ther Pat. 2015;25(12):1397-421.