Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8NLDI)

Drug Name
Endostatin Drug Info
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Cross-matching ID
PubChem CID
187888
CAS Number
CAS 55984-52-6
TTD Drug ID
DM8NLDI

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prolactin receptor (PRLR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LFA-102 DMI4O92 Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Prolanta DMLKF3H Fallopian tube cancer 2C74 Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prolactin receptor (PRLR) TTBPXMA PRLR_HUMAN Modulator [1]

References

1 Prolactin antagonist-endostatin fusion protein as a targeted dual-functional therapeutic agent for breast cancer. Cancer Res. 2003 Jul 1;63(13):3598-604.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1721).
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)