Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8PA2V)

Drug Name

PMID21741839C5 Drug Info

Synonyms

GTPL8670; BDBM50324475; BJA

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Airway trypsin-like protease (TMPRSS11D)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Inhibitor 1 [Colombo et al., 2012]	DMUQHMP	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Airway trypsin-like protease (TMPRSS11D)	TTWHYC8	TM11D_HUMAN	Inhibitor	[1]
Transmembrane protease serine 2 (TMPRSS2)	TT1GM2Z	TMPS2_HUMAN	Inhibitor	[1]

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References

1	Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4860-4.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2420).