Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8RY7G)

Drug Name

3-formyl-4-phenyl-1,2,5-oxadiazole 2-oxide Drug Info

Synonyms

CHEMBL567637; 135733-34-5; 1,2,5-Oxadiazole-3-carboxaldehyde, 4-phenyl-, 2-oxide; 3-formyl-4-phenyl-1,2,5-oxadiazole n2-oxide; ACMC-20mvvi; 3-formyl-4-phenyl-1,2,5-oxadiazole 2-oxide; CTK0F4054; DTXSID00438521; 3-Formyl-4-phenylfurazan 2-oxide; BDBM50300756

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 10352496
CAS Number: CAS 135733-34-5
TTD Drug ID: DM8RY7G

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Cytoplasmic thioredoxin reductase (TXNRD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fotemustine	DMV62ED	Solid tumour/cancer	2A00-2F9Z	Approved	[2]
Spermidine	DMVJNFI	Plaque psoriasis	EA90.0	Phase 3	[2]
Golden phosphorous acetyletic compound 2	DMYJ15A	N. A.	N. A.	Patented	[3]
Terpyridineplatinum(II) complexe 3	DM54EFD	N. A.	N. A.	Patented	[3]
Terpyridineplatinum(II) complexe 4	DMOV86T	N. A.	N. A.	Patented	[3]
Golden phosphorous acetyletic compound 1	DMVAKUI	N. A.	N. A.	Patented	[3]
Acyl oxymethyl acrylamide ester derivative 1	DMXTUE1	N. A.	N. A.	Patented	[3]
PMID27977313-Compound-18	DMIA3GH	N. A.	N. A.	Patented	[3]
Triazole gold complexe 1	DMCWES7	N. A.	N. A.	Patented	[3]
4-aryl quinol derivative 2	DM7TW5Z	N. A.	N. A.	Patented	[3]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytoplasmic thioredoxin reductase (TXNRD1)	TTR7UJ3	TRXR1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schis... J Med Chem. 2009 Oct 22;52(20):6474-83.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	Thioredoxin reductase inhibitors: a patent review.Expert Opin Ther Pat. 2017 May;27(5):547-556.