Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8XJTH)

Drug Name
SPHINX scaffold, 3 Drug Info
Synonyms SPHINX scaffold, 3; SCHEMBL18538650; BDBM221073; US9695160, SPHINX7
Cross-matching ID
PubChem CID
73672854
TTD Drug ID
DM8XJTH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Preclinical Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting SRSF protein kinase 1 (SRPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ZINC959121 DMR0F4H N. A. N. A. Patented [1]
Sphinx DMJF6S0 N. A. N. A. Patented [1]
SPHINX31 DMYZQKC Wet age-related macular degeneration 9B78.3Z Preclinical [2]
PMID15925511C13 DMHY95J Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SRSF protein kinase 1 (SRPK1) TTU3WV6 SRPK1_HUMAN Inhibitor [1]

References

1 Piperazine derivatives for treating disorders. US9695160.
2 Kinase inhibitors: the road ahead. Nat Rev Drug Discov. 2018 May;17(5):353-377.
3 Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3241-6.