Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8ZFS3)

Drug Name

BY-1949 Drug Info

Synonyms

BY-1949; 90158-59-1; 3-Methoxy-11-methyldibenz(b,f)oxazepine-8-carboxylate; AC1L3SM5; SCHEMBL194184; DTXSID60238049; JTZGDJSJVQONAV-UHFFFAOYSA-N; 11-methyl-3-methoxydibenz[b,f][1,4]oxazepine-8-carboxylic acid; Dibenz(b,f)(1,4)oxazepine-8-carboxylic acid, 3-methoxy-11-methyl-; 9-methoxy-6-methylbenzo[b][1,4]benzoxazepine-3-carboxylic acid; 3-methoxy-11-methyldibenzo[b,f][1,4]oxazepin-8-carboxylic acid

Indication

Disease Entry	ICD 11	Status	REF
Cognitive impairment	6D71	Discontinued in Phase 2	[1]

Cross-matching ID

PubChem CID: 146138
CAS Number: CAS 90158-59-1
TTD Drug ID: DM8ZFS3

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting ATP phosphatase (ATPase)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LYC-30937	DMP05GL	Plaque psoriasis	EA90.0	Phase 2	[3]
FR-76830	DM7WGXS	Angina pectoris	BA40	Terminated	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ATP phosphatase (ATPase)	TT5WKM8	NOUNIPROTAC	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001319)
2	An activation of synaptosomal Na+,K(+)-ATPase by a novel dibenzoxazepine derivative (BY-1949) in the rat brain: its functional role in the neurotransmitter uptake systems. J Neurochem. 1992 Jan;58(1):362-8.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	On the mode of cardioprotection produced by a new bradycardic agent, FR 76830, during ischaemia and after reperfusion in the isolated perfused rat heart: a 31P-NMR study. Cardiovasc Res. 1990 Dec;24(12):1008-12.