Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM98F0U)

• Drug Name: 1-[2-(trityloxy)ethoxymethyl]uracil Drug Info
• Synonyms: 1-[2-(trityloxy)ethoxymethyl]uracil; CHEMBL424704; SCHEMBL912787; US8530490, Comparative 1; QEKAGWDUKXATPZ-UHFFFAOYSA-N; BDBM50190553

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 11750725
  TTD Drug ID: DM98F0U

Molecule-Related Drug Atlas

Drug(s) Targeting Bacterial Deoxyuridine triphosphate nucleotidohydrolase (Bact dut)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[2]
2'-deoxyuridylic acid	DMPV1LU	Discovery agent	N.A.	Investigative	[2]
Deoxyuridine-5'-Triphosphate	DMCG5V2	Discovery agent	N.A.	Investigative	[2]
1-[(Z)-4-trityloxy-2-butenyl]uracil	DMIHBFO	Discovery agent	N.A.	Investigative	[1]
2'-deoxyuridine 5'-alpha,beta-imido-diphosphate	DMXV27U	Discovery agent	N.A.	Investigative	[3]
1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil	DMHXAMR	Discovery agent	N.A.	Investigative	[1]
Deoxyuridine-5'-Diphosphate	DMIFMDC	Discovery agent	N.A.	Investigative	[3]
1-(3-tritylaminopropyl)uracil	DMZPJM4	Discovery agent	N.A.	Investigative	[1]
2'-Deoxyuridine 5'-Alpha,Beta-Imido-Triphosphate	DMOHABR	Discovery agent	N.A.	Investigative	[2]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Deoxyuridine triphosphate nucleotidohydrolase (Bact dut)	TTY8KJS	DUT_ECOLI	Inhibitor	[1]

References

• [1] Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem. 2006 Jul 13;49(14):4183-95.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [3] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.