Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9AZKE)

Drug Name

PFFFFF Drug Info

Synonyms

CHEMBL246187

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Galectin-3 (LGALS3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GR-MD-02	DM9QF65	Hypertension	BA00-BA04	Phase 2	[2]
GB0139	DMA8KQR	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[3]
GB0139	DMA8KQR	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[4]
2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide	DM592YS	Discovery agent	N.A.	Investigative	[5]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries. Bioorg Med Chem Lett. 2007 Feb 1;17(3):793-8.
2	Therapy of experimental NASH and fibrosis with galectin inhibitors. PLoS One. 2013 Dec 18;8(12):e83481.
3	An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE). Am J Respir Crit Care Med. 2023 Jan 15;207(2):138-149.
4	Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation. Front Pharmacol. 2022 Aug 8;13:949264.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.