Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9FHV8)

Drug Name

CK-2127107 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Amyotrophic lateral sclerosis	8B60.0	Phase 2	[1]
Spinal muscular atrophy	8B61	Phase 2	[1]
Muscle atrophy	FB32.Y	Phase 1	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Fast skeletal muscle troponin complex (TNNC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CK-2017357	DMJ9ZIY	Amyotrophic lateral sclerosis	8B60.0	Phase 3	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fast skeletal muscle troponin complex (TNNC2)	TTYUMF5	TNNC2_HUMAN	Modulator	[3]

------------------------------------------------------------------------------------

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037810)
3	Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases. Nat Med. 2012 Feb 19;18(3):452-5.