Details of the Drug-Related molecule(s) Interaction Atlas

BDBM50444058 Drug Info

CHEMBL3092769; SCHEMBL16435582; BDBM50444058

Cross-matching ID

PubChem CID

72793043

TTD Drug ID

DM9GLQB

General Information of Drug (ID: DM9GLQB)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting TYRO3 tyrosine kinase receptor (TYRO3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RXDX-106	DM6NVTR	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
BDBM50444062	DMR2UGC	N. A.	N. A.	Patented	[1]
KRDULPYOVRWKMA-UHFFFAOYSA-N	DMRY7KV	N. A.	N. A.	Patented	[3]
BDBM50444059	DMS0EMU	N. A.	N. A.	Patented	[1]
US10053465, 8	DM42XWO	N. A.	N. A.	Patented	[3]
US10053465, 12	DMPM8VB	N. A.	N. A.	Patented	[4]
US10053465, 5	DMV7BF2	N. A.	N. A.	Patented	[4]
LDC1267	DMH7R6L	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TYRO3 tyrosine kinase receptor (TYRO3)	TTIEMFN	TYRO3_HUMAN	Inhibitor	[1]

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References

1	Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity. US9649309.
2	National Cancer Institute Drug Dictionary (drug name RXDX106).
3	Pyrrolopyrimidine derivatives as TAM inhibitors. US10053465.
4	Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors. US9708333.
5	The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014 Mar 27;507(7493):508-12.