General Information of Drug (ID: DM9KCYQ)

Drug Name
L-709,587 Drug Info
Synonyms L-709,587; C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN; 1qpl; DB03621
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5496872
TTD Drug ID
DM9KCYQ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GPI-1485 DM64ZYM Parkinson disease 8A00.0 Phase 2 [2]
SDZ-281-240 DMPZ67G Pruritus EC90 Phase 2 [3]
AP1903 DM2LU8M Transplant rejection NE84 Phase 1/2 [4]
Gpi-1046 DMD5WK4 Parkinson disease 8A00.0 Terminated [5]
MYRISTIC ACID DMYX0BL Discovery agent N.A. Investigative [5]
Heptyl-Beta-D-Glucopyranoside DMPQBN0 Discovery agent N.A. Investigative [6]
4-Hydroxy-2-Butanone DM7BQ65 Discovery agent N.A. Investigative [1]
Methyl Methylsulfinylmethyl Sulfide DMOCXLW Discovery agent N.A. Investigative [1]
Rapamycin Immunosuppressant Drug DM678IB Discovery agent N.A. Investigative [1]
FKB-001 DM9K834 Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
FK506-binding protein 1A (FKBP1A) TTMW94E FKB1A_HUMAN Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42.
3 Clearing of psoriasis by a novel immunosuppressive macrolide. J Invest Dermatol. 1996 Apr;106(4):701-10.
4 Using gene transfer to circumvent off-target effects. Gene Ther. 2008 May;15(10):759-64.
5 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
6 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.