Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9UF02)

Drug Name

Brocresine Drug Info

Synonyms

Brocresine; Brocresin; 555-65-7; 3-(Aminooxymethyl)-6-bromphenol; Brocresinum [INN-Latin]; Brocresina [INN-Spanish]; NSD 1055; Brocresine [USAN:INN:BAN]; UNII-11F6O06WN0; CL 54998; NSD-1055; alpha-(Aminooxy)-6-bromo-m-cresol; C7H8BrNO2; 5-((Aminooxy)methyl)-2-bromophenol; O-)4-Brom-3-hydroxybenzyl)hydroxylamin; BRN 1945736; Phenol, 5-((aminooxy)methyl)-2-bromo-; 4-Bromo-3-hydroxybenzyloxyamine; QNWOSJAGFSUDFE-UHFFFAOYSA-N; 11F6O06WN0; 5-[(Aminooxy)methyl]-2-bromophenol; m-CRESOL, alpha-(AMINOOXY)-6-BROMO-; Brocresina

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11151
CAS Number: CAS 555-65-7
TTD Drug ID: DM9UF02

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Histidine decarboxylase (HDC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lixivaptan	DMDN4ZP	Hyponatraemia	5C72	Phase 3	[2]
ALPHA-FMH	DMP9VXQ	Pruritus	EC90	Phase 1	[3]
AMA	DM5JZUB	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Histidine decarboxylase (HDC)	TTV9GOF	DCHS_HUMAN	Inhibitor	[1]

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References

1	Histamine in brain--its role in regulation of seizure susceptibility. Epilepsy Res. 1991 Nov-Dec;10(2-3):111-8.
2	Clinical pipeline report, company report or official report of Biofrontera (2009).
3	Alpha-Fluoromethylhistidine. Kinetics of uptake and inhibition of histamine synthesis in basophil (2H3) cell cultures. Mol Pharmacol. 1985 Aug;28(2):191-9.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1274).