Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9Y51T)

Drug Name

ISIS-ANGPTL3 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hyperlipidaemia	5C80	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting ANGPTL3 messenger RNA (ANGPTL3 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Vupanorsen	DMN6J18	Hypertriglyceridemia	5C80.1	Phase 2	[3]
ARO-ANG3	DM3PDL8	Dyslipidemia	5C80-5C81	Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ANGPTL3 messenger RNA (ANGPTL3 mRNA)	TT59GO7	ANGL3_HUMAN	Not Available	[2]

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References

1	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.
2	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.
3	Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.
4	ANGPTL3 and Apolipoprotein C-III as Novel Lipid-Lowering Targets. Curr Atheroscler Rep. 2021 Mar 10;23(5):20.