General Information of Drug (ID: DMA3OI4)

Drug Name
US9359293, TA Drug Info
Synonyms SCHEMBL18103200; CHEMBL3892393; BDBM234205; US9359293, TA
Cross-matching ID
PubChem CID
122580129
TTD Drug ID
DMA3OI4

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BDBM50363780 DM46UPM N. A. N. A. Patented [2]
BDBM50363782 DMUQI15 N. A. N. A. Patented [2]
AC1LFGWU DMXI3O0 N. A. N. A. Patented [3]
ZINC915379 DMW9P6U N. A. N. A. Patented [3]
US9359293, TM DM0NIB5 N. A. N. A. Patented [1]
BDBM50363773 DM7TASJ N. A. N. A. Patented [2]
US9359293, TB DMRQ2G4 N. A. N. A. Patented [1]
AC1LOJYQ DMVX9NK N. A. N. A. Patented [3]
AGK2 DM26AMU Discovery agent N.A. Investigative [4]
INDUS-815C DMLJ645 Retinopathy 9B71 Investigative [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
NAD-dependent deacetylase sirtuin-2 (SIRT2) TTLKF5M SIR2_HUMAN Inhibitor [1]

References

1 Methods of treatment using modulators of SIRT2. US9359293.
2 Aroyl thiourea derivatives. US9365508.
3 Small molecule activators of NRF2 pathway. US9737525.
4 Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27;317(5837):516-9.
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2708).