Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMA41DO)

Drug Name
Isunakinra Drug Info
Synonyms EBI-005
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DMA41DO

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-1 receptor (IL1R) TT5BFT0 IL1R1_HUMAN; IL1R2_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04121442) Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors. U.S. National Institutes of Health.
2 Multicenter Study of a Novel Topical Interleukin-1 Receptor Inhibitor, Isunakinra, in Subjects With Moderate to Severe Dry Eye Disease. Eye Contact Lens. 2017 Sep;43(5):287-296.