Details of the Drug-Related molecule(s) Interaction Atlas

Obtusifoldienol Drug Info

Ebericol; Eburicol; 24-Methylenedihydrolanosterol; Q27138657; SCHEMBL4169147; XJLZCPIILZRCPS-ANMPWZFDSA-N; ZINC5440303; (3beta)-24-methylidenelanost-8-en-3-ol; 24-Methylene-24,25-dihydrolanosterol; 24-Methylenelanost-8-en-3-ol #; 24-Methylenelanost-8-en-3beta-ol; 24-Methylenelanostenol; 24-methylene-24-dihydrolanosterol; 24-methylidenelanost-8-en-3beta-ol; 6890-88-6; CHEBI:70315; Lanost-8-en-3-ol, 24-methylene-, (3.beta.)-; Lanost-8-en-3.beta.-ol, 24-methylene-; W2396

Cross-matching ID

PubChem CID

9803310

ChEBI ID

CHEBI:70315

CAS Number

CAS 6890-88-6

TTD Drug ID

DMA63FQ

INTEDE Drug ID

DR2667

General Information of Drug (ID: DMA63FQ)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Metabolized By Cytochrome P450 monooxygenase 51A (cyp51A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lanosterol	DMHN74V	Discovery agent	N.A.	Investigative	[1]
Dihydrolanosterol	DMG0PXI	N. A.	N. A.	Investigative	[1] , [2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 monooxygenase 51A (cyp51A)^{Main DME}	DEVSF75	CP51A_ASPFU	Substrate	[1] , [2]

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References

1	The fungal CYP51s: their functions, structures, related drug resistance, and inhibitors. Front Microbiol. 2019 Apr 24;10:691.
2	Lung colonization by Aspergillus fumigatus is controlled by ZNF77. Nat Commun. 2018 Sep 20;9(1):3835.