Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMA7LUR)

Drug Name

ANTAQ Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Puromycin-sensitive aminopeptidase (NPEPPS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CHR-2797	DMULZ4W	Acute myeloid leukaemia	2A60	Phase 2	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Puromycin-sensitive aminopeptidase (NPEPPS)	TT371QC	PSA_HUMAN	Inhibitor	[1]

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References

1	Fluorescent bioprobes for visualization of puromycin-sensitive aminopeptidase in living cells. Bioorg Med Chem Lett. 2003 Jan 6;13(1):83-6.
2	CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells. Cancer Res. 2008 Aug 15;68(16):6669-79.