Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMADNY3)

Drug Name
SHR-1314 Drug Info
Indication
Disease Entry ICD 11 Status REF
Plaque psoriasis EA90.0 Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DMADNY3

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Interleukin-17 (IL17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Brodalumab DMASDQ6 Plaque psoriasis EA90.0 Approved [2]
Bimekizumab DMR9TF1 Plaque psoriasis EA90.0 Approved [1]
Ixekizumab DMXW92T Plaque psoriasis EA90.0 Approved [3]
CNTO-6785 DM6RQXB Rheumatoid arthritis FA20 Phase 2 [4]
ABT-122 DM23UQ9 Psoriatic arthritis FA21 Phase 2 [5]
CJM112 DMTSVJM Acne vulgaris ED80 Phase 2 [6]
COVA322 DM824EG Psoriasis vulgaris EA90 Phase 1/2a [7]
ABBV-257 DMCZI8L Rheumatoid arthritis FA20 Phase 1 [8]
ALX-0761 DMJ8ACF Psoriasis vulgaris EA90 Phase 1 [7]
SCH-900117 DM7A6R5 Rheumatoid arthritis FA20 Phase 1 [9]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-17 (IL17) TTG0MT6 IL17_HUMAN Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3 Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: a critical appraisal. Br J Dermatol. 2012 Oct;167(4):710-3; discussion 714-5.
4 Targeting the IL-17-T(H)17 pathway. Nat Rev Drug Discov. 2015 Jan;14(1):11-2.
5 DOI: 10.1136/annrheumdis-2015-eular.4042
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7 Bispecific antibodies rise again. Nat Rev Drug Discov. 2014 Nov;13(11):799-801.
8 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
9 Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov. 2012 Oct;11(10):763-76.