Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMALRU9)

Drug Name

Clodinafop Drug Info

Synonyms

Propanoic acid, 2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]-; 87135-08-8; AC1L3BBN; SCHEMBL1535846; CTK3C5537; DTXSID60275833; YUIKUTLBPMDDNQ-UHFFFAOYSA-N; 2-[4-(5-chloro-3-fluoropyridin-2-yl)oxyphenoxy]propanoic acid; 2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid; 2-[4-(5-chloro-3-fluoropyrdin-2-yloxy)phenoxy]propionic acid; 2-[4-[(5-chloro-3-fluoro-2-pyridyl)oxy]phenoxy]propanoic acid; (+)-[4-(5-chloro-3-fluoropyridin-2-yloxy)-phenoxy]-propionic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5483847
ChEBI ID: CHEBI:132841
CAS Number: CAS 114420-56-3
TTD Drug ID: DMALRU9

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Plasmodium Acetyl-CoA carboxylase 1 (Malaria ACC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CP-640186	DMO0PS9	Discovery agent	N.A.	Investigative	[2]
A-80040	DML20N9	Discovery agent	N.A.	Investigative	[3]
AC-8632	DM09BJ4	Parkinson disease	8A00.0	Investigative	[4]
Haloxyfop	DM5SULN	Discovery agent	N.A.	Investigative	[1]
Quizalofop	DM9KMEI	Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium Acetyl-CoA carboxylase 1 (Malaria ACC1)	TTYAWV0	Q9U752_PLAFA	Binder	[1]

------------------------------------------------------------------------------------

References

1	The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51.
2	Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2383-8.
3	Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acet... J Med Chem. 2006 Jun 29;49(13):3770-3.
4	Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science. 2000 Jun 30;288(5475):2379-81.