Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAPIXW)

Drug Name

NGM831 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Aggressive cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
CD85k-Fibronectin interaction (LILRB4-FN1 PPI)	TT6EMVP	LIRB4_HUMAN-FINC_HUMAN	Antagonist	[2]

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References

1	ClinicalTrials.gov (NCT05215574) A Phase 1/1b Dose Escalation/Expansion Study of NGM831 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of NGM Biopharma