Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAY48N)

Drug Name

GPI 18214 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Poly [ADP-ribose] glycohydrolase (PARG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
N-bis-(3-phenyl-propyl)9-oxo-fluorene-2,7-diamide	DMWSDZ9	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Poly [ADP-ribose] glycohydrolase (PARG)	TT39J16	PARG_HUMAN	Inhibitor	[1]

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References

1	Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice. Crit Care Med. 2004 Jun;32(6):1365-74.
2	Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat. Brain Res. 2003 Jul 18;978(1-2):99-103.