Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBOSGN)

Drug Name

RWJ-49968 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Fungal infection	1F29-1F2F	Investigative	[1]

Therapeutic Class

Antifungal Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Bacterial Sporulation kinase A (Bact kinA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RWJ-49815	DMUGZMO	Fungal infection	1F29-1F2F	Terminated	[2]
SK509	DM73SC6	Discovery agent	N.A.	Investigative	[2]
RWJ-61907	DMGUWFJ	Fungal infection	1F29-1F2F	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Sporulation kinase A (Bact kinA)	TTJVCG0	KINA_BACSU	Inhibitor	[1]

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References

1	Antifungal agents: mode of action in yeast cells. Rev Esp Quimioter. 2006 Jun;19(2):130-9.
2	Histidine kinases as targets for new antimicrobial agents. Bioorg Med Chem. 2002 Apr;10(4):855-67.