Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBOZPH)

Drug Name

RX-5902 Drug Info

Synonyms

Microtubule-cell cycle inhibitor (oral, cancer), Rexahn; Piperazine G2/M-specific cell cycle and Bcl inhibitors (oral,cancer), Rexahn

Indication

Disease Entry	ICD 11	Status	REF
Triple negative breast cancer	2C60-2C65	Phase 2	[1]
Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ATP-dependent RNA helicase DDX5 (DDX5)	TTOTSW1	DDX5_HUMAN	Modulator	[3]
Phosphorylated p68 RNA helicase (pDDX5)	TTZKPVC	DDX5_HUMAN	Inhibitor	[1]

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT02003092) RX-5902 Treatment of Subjects With Solid Tumors. U.S. National Institutes of Health.
3	Company report (Rexahn)