General Information of Drug (ID: DMBTL2M)

Drug Name
TP-1454 Drug Info
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Cross-matching ID
PubChem CID
90120714
TTD Drug ID
DMBTL2M

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Pyruvate kinase M2 (PKM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CAP-232 DMR6LXM Renal cell carcinoma 2C90 Phase 2a [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pyruvate kinase M2 (PKM) TT4LOT8 KPYM_HUMAN Activator [2]

References

1 ClinicalTrials.gov (NCT04328740) Phase 1 Study of Oral TP-1454. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Sumitomo Dainippon Pharma.
3 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.