Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBXYKG)

Drug Name
GSK-1362885 Drug Info
Synonyms 1362885
Indication
Disease Entry ICD 11 Status REF
Type-2 diabetes 5A11 Discontinued in Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMBXYKG

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Myophosphorylase (PYGM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flavopiridol DMKSUOI Acute myeloid leukaemia 2A60 Phase 2 [3]
PSN357 DMDOFE7 Type-2 diabetes 5A11 Discontinued in Phase 2 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myophosphorylase (PYGM) TT31JXP PYGM_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT01013766) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK1362885 in Type 2 Diabetics. U.S. National Institutes of Health.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 Pharma & Vaccines. Product Development Pipeline. April 29 2009.
4 PhRMA