Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMC04SR)

Drug Name

LB-100 Drug Info

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Serine/threonine PP2A-alpha (PPP2CA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
VP-102	DM5T4IS	Molluscum contagiosum infection	1E76	Phase 3	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Serine/threonine PP2A (PP2A)	TTRKDL6	NOUNIPROTAC	Inhibitor	[3]
Serine/threonine PP2A-alpha (PPP2CA)	TTHTKNY	PP2AA_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT03027388) Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma. U.S. National Institutes of Health.
2	Inhibition of protein phosphatase 2A enhances cytotoxicity and accessibility of chemotherapeutic drugs to hepatocellular carcinomas. Mol Cancer Ther. 2014 Aug;13(8):2062-72.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)