General Information of Drug (ID: DMC1YR5)

Drug Name
US9493490, C Drug Info
Synonyms US9493490, Example 3; BDBM258594; US9493490, C; US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
Cross-matching ID
PubChem CID
90646682
TTD Drug ID
DMC1YR5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9493490, E DMFCIGE N. A. N. A. Patented [1]
US9493490, D DMUVC25 N. A. N. A. Patented [1]
BDBM50173306 DMSTD28 N. A. N. A. Patented [2]
US9493490, L DMJDTSN N. A. N. A. Patented [1]
PMID24210504C1o DM4LEUT Discovery agent N.A. Investigative [3]
PMID21596927C101 DM7JRHB Discovery agent N.A. Investigative [4]
BetaARKct DMN7DJ5 Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Beta-adrenergic receptor kinase 1 (ADRBK1) TTAZ3MN ARBK1_HUMAN Inhibitor [1]

References

1 Boron-containing small molecules. US9493490.
2 G protein-coupled receptor kinase 2 inhibitors and methods for use of the same. US10023564.
3 Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6711-6.
4 Molecular mechanism of selectivity among G protein-coupled receptor kinase 2 inhibitors. Mol Pharmacol. 2011 Aug;80(2):294-303.
5 Gene-mediated inhibition of the b-adrenergic receptor kinase: a new therapeutic strategy for heart failure. Minerva Cardioangiol. 2001 Dec;49(6):389-94.