Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMC80LV)

Drug Name

ASP1948 Drug Info

Synonyms

PTZ-329

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Neuropilin-1 (NRP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pegaptanib	DMOWEBU	Neovascular age-related macular degeneration	9B78.3Z	Approved	[3]
RG7347	DMOE5NQ	Solid tumour/cancer	2A00-2F9Z	Phase 1	[4]
H-KPPR-OH	DMDINX9	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT04094506) Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
2	National Cancer Institute Drug Dictionary (drug name ASP1948).
3	Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006 Feb;5(2):123-32.
4	Neuropilin-1 as Therapeutic Target for Malignant Melanoma. Front Oncol. 2015; 5: 125.
5	Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010 Mar 11;53(5):2215-26.