Details of the Drug-Related molecule(s) Interaction Atlas

3ts4 Drug Info

N-{3-[4-(4-Phenylthiophen-2-Yl)phenyl]propanoyl}-L-Alpha-Glutamyl-L-Alpha-Glutamyl-Amide; US8691753, 96; 3ts4; SCHEMBL6868348; CHEMBL1232492; BDBM120246; US8691753, 95; N-{3-[4-(4-phenylthiophen-2-yl)phenyl]propanoyl}-L-alpha-glutamyl-L-alpha-glutamine

Cross-matching ID

PubChem CID

46861563

TTD Drug ID

DMCJHK2

General Information of Drug (ID: DMCJHK2)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Matrix metalloproteinase-10 (MMP-10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
EEA	DM5UM8I	N. A.	N. A.	Patented	[1]
EEC	DMR9IE5	N. A.	N. A.	Patented	[1]
CM-352	DMXA8K1	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Matrix metalloproteinase-10 (MMP-10)	TTXLEG7	MMP10_HUMAN	Inhibitor	[1]

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References

1	Pseudodipeptides as MMP inhibitors. US8691753.
2	Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage. J Med Chem. 2015 Apr 9;58(7):2941-57.