Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCZ75T)

Drug Name

DRAFLAZINE Drug Info

Synonyms

Draflazine < Rec INN; R-70380; R-75231; Rac-N-(4-Amino-2,6-dichlorophenyl)-4-[5,5-bis(4-fluorophenyl)pentyl]-2-carbamoylpiperazine-1-acetamide; Rac-2-(Aminocarbonyl)-N-(4-amino-2,6-dichlorophenyl)-4-[5,5-bis(4-fluorophenyl)pentyl]-1-piperazineacetamide; Rac-4'-Amino-4-[5,5-bis(p-fluorophenyl)pentyl]-2-carbamoyl-2',6'-dichloro-1-piperazineacetanilide

Indication

Disease Entry	ICD 11	Status	REF
Cardiac arrhythmias	BC9Z	Discontinued in Phase 2	[1]

Cross-matching ID

PubChem CID: 60849
CAS Number: CAS 120770-34-5
TTD Drug ID: DMCZ75T

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nucleoside transporter (SLC)	TT5BN70	NOUNIPROTAC	Modulator	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4590).
2	Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium. Br J Pharmacol. 1994 May;112(1):137-42.