Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD2L1U)

Drug Name

OBI-888 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Globohexaosylceramide (Globo H)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
OBI-999	DMPB9OD	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Globohexaosylceramide (Globo H)	TT4UXTG	NOUNIPROTAC	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT03573544) This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of OBI Pharma.
3	Preclinical Studies of OBI-999: A Novel Globo H-Targeting Antibody-Drug Conjugate. Mol Cancer Ther. 2021 Jun;20(6):1121-1132.