Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDE3J1)

Drug Name

ISIS 24454 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting ITGA4 messenger RNA (ITGA4 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ATL1102	DM3POT6	Multiple sclerosis	8A40	Phase 2	[2]
MK-0668	DMVBFJP	Discovery agent	N.A.	Investigative	[3]
ISIS 24477	DMCNBIL	Discovery agent	N.A.	Investigative	[1]
ISIS 24448	DMLHQ2J	Discovery agent	N.A.	Investigative	[1]
ISIS 24453	DM45WUZ	Discovery agent	N.A.	Investigative	[1]
ISIS 24475	DMBKZOQ	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	US patent application no. 6,258,790, Antisense modulation of integrin .alpha.4 expression.
2	CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS.Neurology.2014 Nov 11;83(20):1780-8.
3	Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3',5'-dichloro-isonicotinoyl) amino]-(l)-phenylalan... Bioorg Med Chem Lett. 2009 Oct 1;19(19):5803-6.