General Information of Drug (ID: DMDF26N)

Drug Name
Isoquinolin-1-yl-(3-phenyl-propyl)-amine Drug Info
Synonyms CHEMBL289792; Isoquinolin-1-yl-(3-phenyl-propyl)-amine; BDBM50282107
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44288035
TTD Drug ID
DMDF26N

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
(3-Phenyl-propyl)-quinazolin-4-yl-amine DM1C90Y Discovery agent N.A. Investigative [1]
Carpropamid DMBKQ03 Discovery agent N.A. Investigative [2]
2-Hydroxy-N-(3-phenyl-propyl)-benzamide DMWSR13 Discovery agent N.A. Investigative [1]
5-Fluoro-2-hydroxy-N-isopropyl-benzamide DMOI7ME Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fungal Scytalone dehydratase (Fung SDH1) TT64EPS SCYD_MAGO7 Inhibitor [1]

References

1 A diazine heterocycle replaces a six-membered hydrogen-bonded array in the active site of scytalone dehydratase, Bioorg. Med. Chem. Lett. 3(8):1605-1608 (1993).
2 Enzymatic characterization of scytalone dehydratase Val75Met variant found in melanin biosynthesis dehydratase inhibitor (MBI-D) resistant strains of the rice blast fungus. Biosci Biotechnol Biochem.2004 Mar;68(3):615-21.
3 Binding dynamics of two water molecules constrained within the scytalone dehydratase binding pocket. Bioorg Med Chem Lett. 2000 Jan 3;10(1):23-6.