Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDFUBH)

Drug Name

Piperazine derivative 5 Drug Info

Synonyms

PMID26936077-Compound-16

Indication

Disease Entry	ICD 11	Status	REF
Atopic dermatitis	EA80	Patented	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Proteinase activated receptor 2 (PAR2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MEDI0618	DM7GNSY	Osteoarthritis pain	MG30.31	Phase 1	[2]
Imidazopyridazine derivative 8	DMF7NXJ	Inflammation	1A00-CA43.1	Patented	[1]
Piperazine urea derivative 4	DM3K7IM	Inflammation	1A00-CA43.1	Patented	[1]
Piperidine derivative 2	DMHXMB4	Inflammation	1A00-CA43.1	Patented	[1]
Benzimidazole derivative 10	DML3PE4	N. A.	N. A.	Patented	[1]
Benzothiazine-carboxamide compound 2	DMMP2RT	Skin inflammation	EF20.Y	Patented	[1]
Peptide analog 71	DMSEKZG	N. A.	N. A.	Patented	[1]
Amidine compound 3	DMV0QJ4	Inflammation	1A00-CA43.1	Patented	[1]
Benzothiazine-carboxamide compound 4	DMSR918	Skin inflammation	EF20.Y	Patented	[1]
Quinazoline derivative 11	DMAH435	Chronic obstructive pulmonary disease	CA22	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proteinase activated receptor 2 (PAR2)	TTQR74A	PAR2_HUMAN	Antagonist	[1]

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References

1	Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83.
2	Clinical pipeline report, company report or official report of AstraZeneca