Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDFUS8)

Drug Name

ISIS 156473 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting IRAK4 messenger RNA (IRAK4 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 156452	DMCU6RF	Discovery agent	N.A.	Investigative	[1]
ISIS 156453	DMQ9018	Discovery agent	N.A.	Investigative	[1]
N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide	DM0CWPX	Discovery agent	N.A.	Investigative	[2]
ISIS 156451	DMPH2W7	Discovery agent	N.A.	Investigative	[1]
ISIS 156449	DMPB3FH	Discovery agent	N.A.	Investigative	[1]
ISIS 156474	DMCXP9T	Discovery agent	N.A.	Investigative	[1]
ISIS 156475	DMNB4UJ	Discovery agent	N.A.	Investigative	[1]
N-(1H-benzo[d]imidazol-2-yl)-3-cyanobenzamide	DM054NF	Discovery agent	N.A.	Investigative	[2]
ISIS 156472	DM3U0Z6	Discovery agent	N.A.	Investigative	[1]
ISIS 156471	DMM9ARP	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	US patent application no. 6,692,959, Antisense modulation of IL-1 receptor-associated kinase-4 expression.
2	Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.