General Information of Drug (ID: DMDGK83)

Drug Name
NN1841 Drug Info
Synonyms NovoThirteen (TN)
Indication
Disease Entry ICD 11 Status REF
Hemophilia 3B10.0 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMDGK83

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NN8717 DM1PI9G Graft-versus-host disease 4B24 Phase 3 [3]
Tridegin DMUHBSI Thrombosis DB61-GB90 Terminated [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor XIII (F13B) TTAXGIP F13B_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT01253811) Safety and Efficacy of Monthly Replacement Therapy With Recombinant Factor XIII (rFXIII) in Paediatric Subjects With Congenital Factor XIII A-subunit Deficiency. U.S.National Institutes of Health.
2 Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency. J Blood Med. 2014 Jul 9;5:107-13.
3 Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding. Ann Surg Innov Res. 2009; 3: 14.
4 Tridegin, a new peptidic inhibitor of factor XIIIa, from the blood-sucking leech Haementeria ghilianii. Biochem J. 1997 Jun 15;324 ( Pt 3):797-805.