General Information of Drug (ID: DMDINX9)

Drug Name
H-KPPR-OH Drug Info
Synonyms CHEMBL1091089; H-KPPR-OH
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
15858500
TTD Drug ID
DMDINX9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Neuropilin-1 (NRP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pegaptanib DMOWEBU Neovascular age-related macular degeneration 9B78.3Z Approved [2]
RG7347 DMOE5NQ Solid tumour/cancer 2A00-2F9Z Phase 1 [3]
ASP1948 DMC80LV Solid tumour/cancer 2A00-2F9Z Phase 1 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neuropilin-1 (NRP1) TTIPJCB NRP1_HUMAN Inhibitor [1]

References

1 Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010 Mar 11;53(5):2215-26.
2 Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006 Feb;5(2):123-32.
3 Neuropilin-1 as Therapeutic Target for Malignant Melanoma. Front Oncol. 2015; 5: 125.
4 National Cancer Institute Drug Dictionary (drug name ASP1948).