Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDJCIP)

Drug Name

G36 Drug Info

Synonyms

G-36

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting G-protein coupled estrogen receptor 1 (GPER1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Segesterone acetate; ethinyl estradiol	DMFEGB0	Contraception	QA21	Approved	[3]
G1	DMTV42K	Lymphoma	2A80-2A86	Phase 1/2	[4]
G15	DMMEC9D	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled estrogen receptor 1 (GPER1)	TTDSB34	GPER1_HUMAN	Antagonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6480).
2	Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity. J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):358-66.
3	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
4	Virtual and biomolecular screening converge on a selective agonist for GPR30. Nat Chem Biol. 2006 Apr;2(4):207-12.
5	In vivo effects of a GPR30 antagonist. Nat Chem Biol. 2009 Jun;5(6):421-7.