Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDMU01)

Drug Name
PMID24775305C7u Drug Info
Synonyms GTPL8633; BDBM50015362
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
90656796
TTD Drug ID
DMDMU01

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Legumain (LGMN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Legumain-cleavable doxorubicin prodrugs DMEUGZL Solid tumour/cancer 2A00-2F9Z Phase 2/3 [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Legumain (LGMN) TTPTWV5 LGMN_HUMAN Inhibitor [1]

References

1 P3 SAR exploration of biphenyl carbamate based Legumain inhibitors. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2521-4.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2380).