Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDO9AJ)

Drug Name

PMID25313322C15 Drug Info

Synonyms

GTPL7803; BDBM50030783

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting G-protein coupled receptor 39 (GPR39)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GPCR39 pepducins	DM1W5G9	Diabetic complication	5A2Y	Investigative	[2]
PMID24900608C1	DMCL6H3	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled receptor 39 (GPR39)	TTTPCNU	GPR39_HUMAN	Agonist	[1]

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References

1	Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists. ACS Med Chem Lett. 2014 Aug 4;5(10):1114-8.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 105).
3	Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example. ACS Med Chem Lett. 2013 Sep 16;4(11):1079-84.