Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDPN4E)

Drug Name

WO2013110309CA127 Drug Info

Synonyms

A-127; GTPL8169; BDBM50011235

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4)	TT9U4EP	E2AK4_HUMAN	Inhibitor	[2]

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References

1	The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. EMBO J. 2010 Jun 16;29(12):2082-96.
2	Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2. ACS Med Chem Lett. 2014 Feb 12;5(4):282-3.