Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDSNIR)

Drug Name

BBI503 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Cholangiocarcinoma	2C12.10	Phase 2	[1]
Hepatocellular carcinoma	2C12.02	Phase 2	[1]
Ovarian cancer	2C73	Phase 2	[1]
Solid tumour/cancer	2A00-2F9Z	Phase 2	[2]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cancer stemness kinase (CSK)	TTPV9O1	NOUNIPROTAC	Inhibitor	[2]
Serine/threonine-protein kinase (STK)	TTPMIQ9	NOUNIPROTAC	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT02232633) A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancer. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)