Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDUIO4)

Drug Name
AGS-348 Drug Info
Indication
Disease Entry ICD 11 Status REF
Hereditary angioedema 4A00.14 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMDUIO4

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Pyruvate kinase (PK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etavopivat DMXOHYH Sickle-cell disorder 3A51 Phase 2/3 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pyruvate kinase (PK) TTABNSJ NOUNIPROTAC Modulator [2]

References

1 Biopharmaceutical Research Companies Are Developing More Than 430 Medicines for Top Chronic Diseases Affecting Older Americans. Pharmaceutical Research and Manufacturers of America report. 2014.
2 Clinical pipeline report, company report or official report of Agios Pharmaceuticals.
3 Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease. J Pharmacol Exp Ther. 2022 Mar;380(3):210-219.