Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDV8MK)

Drug Name

CALDARET HYDRATE Drug Info

Synonyms

MCC-135; Caldaret hydrate; 5-Methyl-2-(1-piperazinyl)benzenesulfonic acid monohydrate

Indication

Disease Entry	ICD 11	Status	REF
Cardiovascular disease	BA00-BE2Z	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Sodium/calcium exchanger (SLC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SEA-0400	DME69PI	Cerebrovascular ischaemia	8B1Z	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sodium/calcium exchanger (SLC)	TT619TC	NOUNIPROTAC	Modulator	[1]

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References

1	Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. J Pharmacol Sci. 2007 Feb;103(2):222-33.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4617).