Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEMKIS)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting H-ras messenger RNA (HRAS mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 6186	DMH7LPO	Discovery agent	N.A.	Investigative	[2]
ISIS 2502	DMYTXBS	Discovery agent	N.A.	Investigative	[2]
ISIS 13920	DM4PM1G	Solid tumour/cancer	2A00-2F9Z	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer. Clin Cancer Res. 2003 Jan;9(1):115-23.
2	US patent application no. 5,965,722, Antisense inhibition of ras gene with chimeric and alternating oligonucleotides.
3	US patent application no. 7,425,545, Modulation of C-reactive protein expression.