Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEWRXA)

Drug Name
SHP647 Drug Info
Indication
Disease Entry ICD 11 Status REF
Ulcerative colitis DD71 Phase 3 [1]
Crohn disease DD70 Phase 2 [2]
Cross-matching ID
TTD Drug ID
DMEWRXA

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Mucosal addressin cell adhesion molecule 1 (MADCAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SCH-527123 DMPUAOE Chronic obstructive pulmonary disease CA22 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mucosal addressin cell adhesion molecule 1 (MADCAM1) TTBD6I7 MADCA_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT03259334) Efficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Colitis (FIGARO UC 301). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Emerging drugs to treat Crohn's disease. Expert Opin Emerg Drugs. 2007 Mar;12(1):49-59.