Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMF3X40)

Drug Name
PMID28766366-Compound-Scheme21Right Drug Info
Cross-matching ID
PubChem CID
53390843
TTD Drug ID
DMF3X40

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Dual-specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Left DMWTRUK N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme16DMAT DMQ5UEA N. A. N. A. Patented [1]
leucettine L41 DMBYND6 Discovery agent N.A. Investigative [2]
Drug(s) Targeting Dual-specificity tyrosine-phosphorylation regulated kinase 1B (DYRK1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID28766366-Compound-Scheme21Left DMWTRUK N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065bottom DMO4Q95 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070upper DMGAQR5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT1610 DMMZGC8 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT5372 DM0O18N N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-2 DM7OGWH N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065upper DMVJDRI N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070bottom DMQV6R0 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme4Upper DMPH4JV N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Left DMWTRUK N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
TG003 DMP4HR2 Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065bottom DMO4Q95 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme16DMAT DMQ5UEA N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070upper DMGAQR5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT1610 DMMZGC8 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT5372 DM0O18N N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-2 DM7OGWH N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Dual-specificity tyrosine-phosphorylation regulated kinase 3 (DYRK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Left DMWTRUK N. A. N. A. Patented [1]
PMID24900749C1a DMZPUSO Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A) TTSBVFO DYR1A_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 1B (DYRK1B) TTYGQ8A DYR1B_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) TT84OS6 DYRK2_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 3 (DYRK3) TTV4EX0 DYRK3_HUMAN Inhibitor [1]

References

1 Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Expert Opin Ther Pat. 2017 Nov;27(11):1183-1199.
2 Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. J Med Chem. 2011 Jun 23;54(12):4172-86.
3 Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5.