Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMF6V8W)

Drug Name

HALOPEMIDE Drug Info

Synonyms

Halopemide; 59831-65-1; UNII-65Q28TV0ZY; R 34,301; MLS003171133; 65Q28TV0ZY; CHEMBL245621; R-34301; N-(2-(4-(5-Chloro-2-oxo-1-benzimidazolinyl)piperidino)ethyl)-p-fluorobenzamide; Halopemida; Halopemidum; Halopemide [USAN:INN]; Halopemidum [INN-Latin]; Halopemida [INN-Spanish]; C21H22ClFN4O2; N-[2-[4-(5-Chloro-2-oxo-1-benzimidazolinyl)piperidino]ethyl]-p-fluorobenzamide; Halopemide, 8; NSC 354856; Halopemide (USAN/INN); AC1L23CG; R 34301; MLS006012046; cid_65490; SCHEMBL121267; Halopemide, > CTK8G0128; AOB5520

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 65490
CAS Number: CAS 59831-65-1
TTD Drug ID: DMF6V8W

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Phospholipase D1 (PLD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9127005, P2C	DMMT98V	N. A.	N. A.	Patented	[2]
US9453017, 1	DMVQ3IX	N. A.	N. A.	Patented	[3]
US9127005, P2B	DM3R7BT	N. A.	N. A.	Patented	[2]
ML272	DMNEY58	N. A.	N. A.	Patented	[3]
US9127005, P0L	DMKLYCV	N. A.	N. A.	Patented	[2]
US9453017, 2	DMPH05Y	N. A.	N. A.	Patented	[3]
1-(pyridin-2-yl)piperazine	DMKE7FG	Discovery agent	N.A.	Investigative	[4]
1-(pyridin-4-yl)piperazine	DM78AJ1	Discovery agent	N.A.	Investigative	[4]
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⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phospholipase D (PLD)	TTQW170	NOUNIPROTAC	Inhibitor	[1]
Phospholipase D1 (PLD1)	TT3T17P	PLD1_HUMAN	Inhibitor	[1]

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References

1	Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17.
2	Isoform selective phospholipase D inhibitors. US9127005.
3	Antiviral therapies with phospholipase D inhibitors. US9453017.
4	Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privil... Bioorg Med Chem Lett. 2009 Apr 15;19(8):2240-3.